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Search Results for " bone destruction "

5

Compounds

Cat No. Product Name Synonyms Targets
T8550 NDMC101 Others , NF-κB , Proteasome
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.
T76711 Golimumab MK-8259,SCH 900259,CNTO-148 TNF
Golimumab (CNTO-148) is a potent humanized anti-TNFα IgG1κ monoclonal antibody.Golimumab has anti-inflammatory and anticancer activity, inhibits the production of IL-6 and IL-1β, and induces apoptosis.Golimumab can be us...
T36127 TNF-α Antagonist
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact sit...
T37413 Calcitonin (salmon) (trifluoroacetate salt)
Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. It belongs to the calcitonin family of peptides, which also includes amylin , calcitonin gene-related peptide , and adrenomedu...
T76786 Cabiralizumab
Cabiralizumab (FPA 008), an anti-CSF1R monoclonal antibody (MAb), promotes T cell infiltration and boosts antitumor immune responses. It also prevents osteoclast activation, thereby inhibiting bone destruction, and is ut...
TargetMol